包装 价格 库存 - 促销价
2.5L     RMB     0
Acetonitrile, LC-MS 	乙腈,LC-MS

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  • Mol. Formula: CH3CN
  • Mol. Weight: 41.05
  • Refractive index: 1.3430 to 1.3460
  • Boiling Point: 81—82 °C ((lit.))
  • Density: 0.782 g/mL at 25 °C
  • Melting Point: -48 °C (lit.)
  • Flash Point: 10°C(lit.)
  • TSCA: Yes
  • Autoignition Point: 973 °F
  • Vapor Density: 1.41 (vs air)
  • Vapor Pressure: 72.8 mmHg
  • Solubility: MISCIBLE
  • Appearance: {Chemicalbook} liquid {...
Chemical NameAcetonitrile
Synonym
  • Ethyl nitrile
  • RCRA waste number U003
  • Methane, cyano-
  • Methanecarbonitrile
  • 乙腈 溶液
CAS Number75-05-8
PubChem Substance ID 24885473
EC Number200-835-2
Beilstein Registry Number4124158
MDL NumberMFCD00001878
Reaxys-RN741857
Merck Number70
Chemical Name Translation乙腈
Wiswesser Line NotationNC1
LabNetwork Molecule IDLN00162999
GHS Symbol
WGK Germany2
Hazard Codes
  • F,Xi,Xn,T
Hazard statements
  • H319 Causes serious eye irritation 严重刺激眼睛
  • H225 Highly flammable liquid and vapour 高度易燃液体和蒸气
  • H302+312+332
  • H332 Harmful if inhaled 吸入有害
  • H302 Harmful if swallowed 吞食有害
Personal Protective Equipment
  • Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
RTECSAL7700000
Precautionary statements
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P210280305+351+338
  • P201 Obtain special instructions before use. 使用前获取专门指示。
  • P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking. 远离热源/火花/明火/热的表面。——禁止吸烟。
Signal word
Safety Statements
  • S36/37 Wear suitable protective clothing and gloves 穿戴适当的防护服和手套;
  • S16 Keep away from sources of ignition - No smoking 远离火源,禁止吸烟;
Risk Statements
  • R10 Flammable 易燃
  • R11 Highly flammable 非常易燃
  • R23/24/25 Toxic by inhalation, in contact with skin and if swallowed 吸入,皮肤接触及吞食都有毒
  • R20/21/22 Harmful by inhalation, in contact with skin and if swallowed 吸入、皮肤接触和不慎吞咽有害
  • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
  • R41 Risk of serious damage to eyes 有严重损伤眼睛的危险
  • R36 Irritating to eyes 刺激眼睛
  • R24 Toxic in contact with skin 与皮肤接触有毒
  • R20/22 Harmful by inhalation and if swallowed 吸入和不慎吞咽有害
UN Number
Packing GroupII
Storage condition
  • 密封阴凉处保存。
  • 2-8°C
  • 免阳光和紫外线照射,4℃下冷藏保存
  • 充氩保存
Hazard Class3
TYPE OF TEST : TCLo - Lowest published toxic concentration ROUTE OF EXPOSURE : Inhalation SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 400 ppm/6H/2Y-I TOXIC EFFECTS : Tumorigenic - equivocal tumorigenic agent by RTECS criteria Liver - tumors REFERENCE : NTPTR* National Toxicology Program Technical Report Series. (Research Triangle Park, NC 27709) No.206- Volume(issue)/page/year: NTP-TR-447,1996
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 3500 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : 85GMAT "Toxicometric Parameters of Industrial Toxic Chemicals Under Single Exposure," Izmerov, N.F., et al., Moscow, Centre of International Projects, GKNT, 1982 Volume(issue)/page/year: -,16,1982
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Parenteral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 1100 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : 85GMAT "Toxicometric Parameters of Industrial Toxic Chemicals Under Single Exposure," Izmerov, N.F., et al., Moscow, Centre of International Projects, GKNT, 1982 Volume(issue)/page/year: -,16,1982
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 4480 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : 85GMAT "Toxicometric Parameters of Industrial Toxic Chemicals Under Single Exposure," Izmerov, N.F., et al., Moscow, Centre of International Projects, GKNT, 1982 Volume(issue)/page/year: -,16,1982
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 850 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : JOCMA7 Journal of Occupational Medicine. (Chicago, IL) V.1-9, 1957-67. For publisher information, see:JJOMDZ Volume(issue)/page/year: 1,634,1959
TYPE OF TEST
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TYPE OF TEST : Sex chromosome loss and nondisjunction ROUTE OF EXPOSURE : Inhalation TEST SYSTEM : Insect - Drosophila melanogaster DOSE/DURATION : 131 ppm REFERENCE : MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 259,165,1991
TYPE OF TEST : Sex chromosome loss and nondisjunction TEST SYSTEM : Yeast - Saccharomyces cerevisiae DOSE/DURATION : 47600 ppm REFERENCE : MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 149,339,1985
TYPE OF TEST : Sister chromatid exchange TEST SYSTEM : Rodent - hamster Ovary DOSE/DURATION : 5 gm/L REFERENCE : EMMUEG Environmental and Molecular Mutagenesis. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.10- 1987- Volume(issue)/page/year: 10(Suppl 10),1,1987
TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - hamster DOSE : 400 mg/kg SEX/DURATION : female 8 day(s) after conception TOXIC EFFECTS : Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants) REFERENCE : TJADAB Teratology, The International Journal of Abnormal Development. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.1- 1968- Volume(issue)/page/year: 27,313,1983
TYPE OF TEST : TCLo - Lowest published toxic concentration ROUTE OF EXPOSURE : Inhalation SPECIES OBSERVED : Rodent - hamster DOSE : 8000 ppm/1H SEX/DURATION : female 8 day(s) after conception TOXIC EFFECTS : Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus) Reproductive - Specific Developmental Abnormalities - musculoskeletal system REFERENCE : TJADAB Teratology, The International Journal of Abnormal Development. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.1- 1968- Volume(issue)/page/year: 27,313,1983
TYPE OF TEST : TCLo - Lowest published toxic concentration ROUTE OF EXPOSURE : Inhalation SPECIES OBSERVED : Rodent - hamster DOSE : 5000 ppm/1H SEX/DURATION : female 8 day(s) after conception TOXIC EFFECTS : Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants) Reproductive - Specific Developmental Abnormalities - Central Nervous System REFERENCE : TJADAB Teratology, The International Journal of Abnormal Development. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.1- 1968- Volume(issue)/page/year: 27,313,1983
TYPE OF TEST :
  • 乙腈最主要的用途是作溶剂。在石油工业中用于从石油烃中除去焦油、酚等物质的溶剂。在油脂工业中用作从动植物油中抽提脂肪酸的溶剂,在医药上用于甾族类药物的再结晶的反应介质。乙腈是医药(维生素B1),香料的中间体,是制造均三嗪氮肥增效剂的原料。也用作酒精的变性剂。此外,还可以用于合成乙胺、乙酸等,并在织物染色、照明工业中也有许多用途。
  • Polar aprotic solvent for a wide variety of reactions, including nucleophilic substitutions, oxidations, reductions and organometallic reactions. Widely used with crown ethers for the generation of 'naked' anions from their salts; see, e.g. 18-Crown-6, A11249. Preferred solvent for RuO4 oxidations, due to its coordinating ability; see Ruthenium(III)­ chloride hydrate, 11043.
  • For use in the mild conversion of amides to nitriles, see Benzamide, A10501.
  • Undergoes the Ritter reaction with alcohols or olefins in the presence of acid to give N-substituted acetamides. For benzylic alcohols, modified conditions employing boron trifluoride etherate give high yields: Synth. Commun., 24, 601 (1994). For an example, see 4-Methyl­benzyl­ alcohol, A15315.
  • Short: II/14a
  • Short: II/19a
  • Merck: 14,55 / Merck 14,70
  • 部分产品数据参考 LabNovo , 请谨慎使用并以实际实验测量值为准。