• 超干溶剂
  • HPLC气相顶空
  • HPLC
  • LC-MS
  • 卡尔费休冠军国际cmp
  • 当量溶液
  • 电导率标准溶液
  • pH缓冲液
  • 农残溶剂
  • 原子吸收标准溶液
  • ICP标准溶液
  • 阴离子标准溶液
  • 无机盐
  • 其他
  • 离子对冠军国际cmp
  • 稳定同位素
  • 紫外-可见吸收光谱
  • 品牌 INFI
  • 编号 H27161
  • 规格 99.9%, SpcDry, Water≤50 ppm (by K.F.), SpcSeal
  • CAS  67-66-3
  • MDL Number  MFCD00000826
  • 易制毒化学品
    Chloroform
三氯甲烷

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  • H27161 MSDS

  • Mol. Formula: CHCl3
  • Mol. Weight: 119.38
  • Refractive index: n20/D 1.445(lit.)
  • Boiling Point: 60.5-61.5 °C(lit.)
  • Density: 1.492 g/mL at 25 °C(lit....
  • Melting Point: -63 °C(lit.)
  • TSCA: Yes
  • Vapor Density: 4.1 (vs air)
  • Vapor Pressure: 160 mmHg ( 20 °C)
  • Solubility: 8 G/L (20 ºC)
  • Flash Point: 60.5-61.5°C
  • Stability: 对光敏感
  • Chemical Name
    Chloroform
    Synonym
  • Trichloromethane
  • CHLOROFORM
  • 氯仿, SPECTROPHOTOMETRIC GRADE, 99.5+%
  • 三氯甲烷( 易制毒化学品,禁止定购)
  • Trichlormethan
  • 氯仿
  • Triclorometano
  • 三氯甲烷
  • METHYLIDYNE TRICHLORIDE
  • Formyl trichloride
  • HCC20
  • Methane,trichloro-
  • RCRA waste number U044
  • 氯仿,三氯甲烷,哥罗念头
  • 氯仿溶液
  • freon20
  • 氯仿 99.5% (GC)
  • Freon 20
  • 哥罗仿,氯仿
  • TRICHLOROMETHANE
  • 氯仿;氯仿溶液
  • Cloroformio
  • AKOS BBS-00004224
  • 氯仿, 不含乙醇, 99+%, .含大约 50PPM戊烯作稳定剂
  • Trichloroform
  • SOLVENT MC
  • Methylidyne trichloride 三氯甲烷
  • formyltrichloride
  • 哥罗仿;氯仿
  • Methane, trichloro-
  • Methane trichloride
  • 氯仿, HPLC GRADE, 99.5+% MIN, 戊烯作稳定剂
  • chloroform(trichloromethane)
  • 三氯甲烷 054-01 [6]
  • CHCl3
  • 氯仿, ENVIRONMENTAL GRADE, 99.8+%, 乙醇作稳定剂
  • chloroforme(french)
  • R 20
  • CHLOROFORM 5000
  • 氯仿, 99%, 以大约 1%乙醇作稳定剂
  • R 20 (Refrigerant)
  • 氯仿, ACS, 99.8+%
  • NCI-C02686
  • Trichloormethaan
  • Methyl trichloride
  • 氯仿, HPLC GRADE, 99.5+% MIN
  • 哥罗仿
  • Chloroform
  • Chloroforme
  • Methenyl trichloride
  • 氯仿 溶液
  • CAS Number
    67-66-3
    PubChem Substance ID
    24871551
    EC Number
    200-663-8
    Beilstein Registry Number
    1731042
    MDL Number
    MFCD00000826
    Merck Number
    14,2141
    Chemical Name Translation
    三氯甲烷
    Wiswesser Line Notation
    GYGG
    GHS Symbol
    WGK Germany
    3
    Hazard Codes
  • Xn
  • F,Xn
  • F,Xi
  • Xn,F,T
  • Hazard statements
  • H315 Causes skin irritation 会刺激皮肤
  • H331 Toxic if inhaled 吸入中毒
  • H336 May cause drowsiness or dizziness 肯能导致嗜睡或头晕
  • H302 Harmful if swallowed 吞食有害
  • H351 Suspected of causing cancer 怀疑致癌
  • H319 Causes serious eye irritation 严重刺激眼睛
  • H372 Causes damage to organs through prolonged or repeated exposure 长期或频繁接触会损伤器官
  • H225 Highly flammable liquid and vapour 高度易燃液体和蒸气
  • H361d Suspected of damaging the unborn child 怀疑对未出生婴儿造成伤害
  • H373 May causes damage to organs through prolonged or repeated exposure 长期或频繁接触可能会损伤器官
  • Personal Protective Equipment
  • Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US)
  • RTECS
    FS9100000
    Precautionary statements
  • P260 Do not breathe dust/fume/gas/mist/vapours/spray. 不要吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P304+340+312
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking. 远离热源/火花/明火/热的表面。——禁止吸烟。
  • P370+378 In case of fire: Use … for extinction. 如果发生火灾:使用...灭火。
  • P403+235 Store in a well-ventilated place. Keep cool. 存放在通风良好的地方。保持凉爽。
  • P305+351+338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. 如接触到眼睛:小心地用水冲洗几分钟。如果佩戴隐形眼镜并容易取出的话,取出隐形眼镜。继续冲洗。
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P201 Obtain special instructions before use. 使用前获取专门指示。
  • P403+233 Store in a well-ventilated place. Keep container tightly closed. 存放在通风良好的地方。保持容器密闭。
  • P308+313 IF exposed or concerned: Get medical advice/attention. 如接触到或有疑虑:求医/就诊。
  • P311 Call a POISON CENTER or doctor/physician. 呼叫解毒中心或医生/医师。
  • P281 Use personal protective equipment as required. 使用所需的个人防护装备。
  • Signal word
  • Danger
  • UN Number
  • UN 1888 6.1/PG 3
  • Risk Statements
  • R11 Highly flammable 非常易燃
  • R36/38 Irritating to eyes and skin 对眼睛和皮肤有刺激性
  • R40 Limited evidence of a carcinogenic effect 有限证据表明其致癌作用
  • R48/20/22
  • R63 Possible risk of harm to the unborn child 可能危害未出生婴儿
  • R20/22 Harmful by inhalation and if swallowed 吸入和不慎吞咽有害
  • R36 Irritating to eyes 刺激眼睛
  • R66 Repeated exposure may cause skin dryness or cracking 反复接触可能导致皮肤干燥或皴裂
  • R67 Vapours may cause drowsiness and dizziness 蒸汽可能导致嗜睡和昏厥
  • R20 Harmful by inhalation 吸入有害
  • R22 Harmful if swallowed 吞咽有害
  • R41 Risk of serious damage to eyes 有严重损伤眼睛的危险
  • R23/24/25 Toxic by inhalation, in contact with skin and if swallowed 吸入,皮肤接触及吞食都有毒
  • R39/23/24/25 Toxic: danger of very serious irreversible effects through inhalation, in contact with skin and if swallowed 毒性:吸入,皮肤接触和吞食都会产生十分严重的不可逆危险
  • R37/38 Irritating to respiratory system and skin 对呼吸系统和皮肤有刺激性
  • R45 May cause cancer 可能致癌
  • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
  • R46 May cause inheritable genetic damage 可能引起遗传基因损害
  • R38 Irritating to skin 刺激皮肤
  • Safety Statements
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后,立即用大量水冲洗并征求医生意见;
  • S36/37 Wear suitable protective clothing and gloves 穿戴适当的防护服和手套;
  • S16 Keep away from sources of ignition - No smoking 远离火源,禁止吸烟;
  • S33 Take precautionary measures against static discharges 对静电采取预防措施;
  • S60 This material and its container must be disposed of as hazardous waste 该物质及其容器必须作为危险废物处置;
  • S9 Keep container in a well-ventilated place 保持容器在通风良好的场所;
  • S23 Do not breathe gas/fumes/vapour/spray (appropriate wording to be specified by the manufacturer) 不要吸入气体/烟雾/蒸汽/喷雾;
  • S36 Wear suitable protective clothing 穿戴适当的防护服;
  • S7 Keep container tightly closed 保存在严格密闭容器中;
  • S53 Avoid exposure - obtain special instructions before use 避免接触,使用前获得特别指示说明;
  • S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时,立即求医(可能时出示标签);
  • S25 Avoid contact with eyes 避免眼睛接触;
  • S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护;
  • Packing Group
    Hazard Class
    6.1
    Storage condition
  • 储存温度2-8℃
  • 2-8°C
  • 密封避光阴凉处保存。
  • Restrict
  • 易制毒化学品
  • Warnings
  • 危化品目录(2015)
  • TYPE OF TEST            : TD - Toxic dose (other than lowest)
    ROUTE OF EXPOSURE       : Oral
    SPECIES OBSERVED        : Rodent - rat
    DOSE/DURATION           : 98 gm/kg/78W-I
    TOXIC EFFECTS :
       Tumorigenic - neoplastic by RTECS criteria
       Kidney, Ureter, Bladder - Kidney tumors
       Endocrine - thyroid tumors
    REFERENCE :
       NCITR* National Cancer Institute Carcinogenesis Technical Report Series.
       (Bethesda, MD)  No.0-205. For publisher information, see NTPTR*.
       Volume(issue)/page/year: NCI-TR-0,1976

    TYPE OF TEST            : TDLo - Lowest published toxic dose
    ROUTE OF EXPOSURE       : Oral
    SPECIES OBSERVED        : Rodent - rat
    DOSE/DURATION           : 13832 mg/kg/2Y-C
    TOXIC EFFECTS :
       Tumorigenic - Carcinogenic by RTECS criteria
       Blood - leukemia
    REFERENCE :
       FAATDF Fundamental and Applied Toxicology.  (Academic Press, Inc., 1 E.
       First St., Duluth, MN 55802) V.1-    1981-  Volume(issue)/page/year:
       5,760,1985

    TYPE OF TEST            : TD - Toxic dose (other than lowest)
    ROUTE OF EXPOSURE       : Oral
    SPECIES OBSERVED        : Rodent - rat
    DOSE/DURATION           : 70 gm/kg/78W-I
    TOXIC EFFECTS :
       Tumorigenic - neoplastic by RTECS criteria
       Kidney, Ureter, Bladder - Kidney tumors
       Endocrine - thyroid tumors
    REFERENCE :
       NCITR* National Cancer Institute Carcinogenesis Technical Report Series.
       (Bethesda, MD)  No.0-205. For publisher information, see NTPTR*.
       Volume(issue)/page/year: NCI-TR-0,1976

    {haz

    TYPE OF TEST            : TD - Toxic dose (other than lowest)
    ROUTE OF EXPOSURE       : Oral
    SPECIES OBSERVED        : Rodent - rat
    DOSE/DURATION           : 58968 mg/kg/2Y-C
    TOXIC EFFECTS :
       Tumorigenic - neoplastic by RTECS criteria
       Endocrine - thyroid tumors
       Blood - tumors
    REFERENCE :
       FAATDF Fundamental and Applied Toxicology.  (Academic Press, Inc., 1 E.
       First St., Duluth, MN 55802) V.1-    1981-  Volume(issue)/page/year:
       5,760,

    TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
    ROUTE OF EXPOSURE       : Oral
    SPECIES OBSERVED

    TYPE OF TEST            : LCLo - Lowest published lethal concentration
    ROUTE OF EXPOSURE       : Inhalation
    SPECIES OBSERVED        : Amphibian - frog
    DOSE/DURATION           : 6 gm/m3
    TOXIC EFFECTS :
       Details of toxic effects not reported other than lethal dose value
    REFERENCE :
       AEXPBL Archiv fuer Experimentelle Pathologie und Pharmakologie.  (Leipzig,
       Ger. Dem. Rep.)  V.1-109, 1873-1925.  For publisher information, see NSAPCC.
        Volume(issue)/page/year: 97,86,1923

    TYPE OF TEST            : TCLo - Lowest published toxic concentration
    ROUTE OF EXPOSURE       : Inhalation
    SPECIES OBSERVED        : Human
    DOSE/DURATION           : 10 mg/m3/1Y
    TOXIC EFFECTS :
       Behavioral - anorexia (human)
       Gastrointestinal - nausea or vomiting
       Gastrointestinal - other changes
    REFERENCE :
       IRGGAJ Internationales Archiv fuer Gewerbepathologie und Gewerbehygiene.
       (Heidelberg, Fed. Rep. Ger.)  V.19-25, 1962-69.  For publisher information,
       see IAEHDW.  Volume(issue)/page/year: 24,127,1967

    TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
    ROUTE OF EXPOSURE       : Subcutaneous
    SPECIES OBSERVED        : Rodent - mouse
    DOSE/DURATION           : 704 mg/kg
    TOXIC EFFECTS :
       Details of toxic effects not reported other than lethal dose value
    REFERENCE :
       JPETAB Journal of Pharmacology and Experimental Therapeutics.  (Williams &
       Wilkins Co., 428 E. Preston St., Baltimore, MD 21202)  V.1-    1909/10-
       Volume(issue)/page/year: 123,224,1958

    TYPE OF TEST            : LC50 - Lethal concentration, 50 percent kill
    ROUTE OF EXPOSURE       : Inhalation
    SPECIES OBSERVED        : Rodent - rat
    DOSE/DURATION           : 47702 mg/m3/4H
    TOXIC EFFECTS :
       Details of toxic effects not reported other than lethal dose value
    REFERENCE :
       ENVRAL Environmental

    TYPE OF TEST            : Mutation test systems - not otherwise specified
    TEST SYSTEM             : Rodent - hamster Fibroblast
    DOSE/DURATION           : 1 pph
    REFERENCE :
       ANESAV Anesthesiology.  (Lippincott/Harper, Journal Fulfillment Dept., 2350
       Virginia Ave., Hagerstown, MD 21740)  V.1-    1940- Volume(issue)/page/year:
       43,21,1975

    TYPE OF TEST            : Sister chromatid exchange
    TEST SYSTEM             : Human Lymphocyte
    DOSE/DURATION           : 10 mmol/L
    REFERENCE :
       ENVRAL Environmental Research.  (Academic Press, Inc., 1 E. First St.,
       Duluth, MN 55802) V.1-    1967-  Volume(issue)/p

    {haz

    TYPE OF TEST            : Sister chromatid exchange
    ROUTE OF EXPOSURE       : Oral
    TEST SYSTEM             : Rodent - mouse
    DOSE/DURATION           : 200 mg/kg/4D (Intermittent)
    REFERENCE :
       ENVRAL Environmental Research.  (Academic Press, Inc., 1 E. First St.,
       Duluth, MN 55802) V.1-    1967-  Volume(issue)/page/year: 32,72,1983

    TYPE OF TEST            : Mutation test systems - not otherw

    TYPE OF TEST            : Sister chromatid exchange
    ROUTE OF EXPOSURE       : Inhalation
    TEST SYSTEM             : Rodent - mouse
    DOSE/DURATION           : 300 ppm/6H
    REFERENCE :
       IGAYAY Igaku No Ayumi.  Progress in Medicine.  (Ishiyaku Shuppan K.K.,
       1-7-10, Honkomagom, Bunkyo-ku, Tokyo, Japan)  V.1-    1946-
       Volume(issue)/page/year: 122,978,1982

    TYPE OF TEST            : DNA inhibition
    TEST SYSTEM             : Human HeLa cell
    DOSE/DURATION           : 19 mmol/L
    REFERENCE :
       CRNGDP Carcinogenesis (London). (Oxford Univ. Press, Pinkhill House,
       Southfield Road, Eynsham,

    TYPE OF TEST            : DNA adduct
    TEST SYSTEM             : Mammal - species unspecified Lymphocyte
    DOSE/DURATION           : 1 mmol/L
    REFERENCE :
       TOLED5 Toxicology Letters.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
       Amsterdam, Netherlands) V.1-    1

    TYPE OF TEST            : TDL

    TYPE OF TEST            : TCLo - Lowest published toxic concentration
    ROUTE OF EXPOSURE       : Inhalation
    SPECIES OBSERVED        : Rodent - rat
    DOSE                    : 30 ppm/7H
    SEX/DURATION            : female 6-15 day(s) after conception
    TOXIC EFFECTS :
       Reproductive - Fertility - other measures of fertility
       Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death,
       e.g., stunted fetus)
       Reproductive - Specific Developmental Abnormalities - musculoskeletal system
    REFERENCE :
       TXAPA9 Toxicology and Applied Pharmacology.  (Academic Press, Inc., 1 E.
       First St., Duluth, MN 55802) V.1-    1959-  Volume(issue)/page/year:
       28,442,1974

    TYPE OF TEST            : TCLo - Lowest published toxic concentration
    ROUTE OF EXPOSURE       : Inhalation
    SPECIES OBSERVED        : Rodent - rat
    DOSE                    : 20100 ug/m3/1H
    SEX/DURATION            : female 7-14 day(s) after conception
    TOXIC EFFECTS :
       Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death,
       e.g., stunted fetus)
       Reproductive - Effects on Embryo or Fetus - fetal death
    REFERENCE :
       NTIS** National Technical Information Service.  (Springfield, VA 22161)
       Formerly U.S. Clearinghouse for Scientific & Technical Information.
       Volume(issue)/page/year: PB277-077

    TYPE OF TEST            : TDLo - Lowest published toxic dose
    ROUTE OF EXPOSURE       : Oral
    SPECIES OBSERVED        : Rodent - rat
    DOSE                    : 4 gm/kg
    SEX/DURATION            : female 6-15 day(s) after conception
    TOXIC EFFECTS :
       Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death,
       e.g., stunted fetus)
    REFERENCE :
       JPFCD2 Journal of Environmental Science and Health, Part B: Pesticides, Food
       Contaminants, and Agricultural Wastes.  (Marcel Dekker, 270 Madison Ave.,
       New York, NY 10016)  V.B11-    1976-  Volume(issue)/page/year: 18,333,1983

  • 脂肪、橡胶、树脂、生物碱、油类、蜡、磷和碘的溶剂,广泛用于提取各种带色化合物,校正温度计,色谱分析用溶剂,清洁洗涤剂,测定血清中无机磷,肝功能试验的防腐剂,测钴、锰、铱、碘、磷的提取剂。冠军国际betcmp官方网站合成。
  • Merck: 14,2141 Beilstein: 1,IV,42
  • For example of use in the generation of dichlorocarbene under phase-transfer catalysis, see: Org. Synth. Coll., 7, 12 (1990). See also Bromoform, A11904.
  • Merck: 14,2141
  • In the presence of base, phenols undergo formylation predominantly in the ortho-position, to give salicylaldehyde derivatives (the Reimer-Tiemann reaction). The mechanism probably involves dichlorocarbene, and yields are generally rather low. For an example, see: Org. Synth. Coll., 3, 463 (1955); review: Org. React., 28, (1982). Improved procedures have been reported: Synth. Commun., 18, 2095 (1988); and, using ultrasound: Synth. Commun., 20, 609 (1990); for an example, see 4-Chlorophenol, A15602.
  • For example of use in the generation of dichlorocarbene under phase-transfer catalysis, see: Org. Synth. Coll., 7, 12 (1990). See also Bromoform, A11904.
  • In the presence of base, phenols undergo formylation predominantly in the ortho-position, to give salicylaldehyde derivatives (the Reimer-Tiemann reaction). The mechanism probably involves dichlorocarbene, and yields are generally rather low. For an example, see: Org. Synth. Coll., 3, 463 (1955); review: Org. React., 28, (1982). Improved procedures have been reported: Synth. Commun., 18, 2095 (1988); and, using ultrasound: Synth. Commun., 20, 609 (1990); for an example, see 4-Chlorophenol, A15602.
  • 部分产品数据参考 LabNovo , 请谨慎使用并以实际实验测量值为准。