• 超干溶剂
  • HPLC气相顶空
  • HPLC
  • LC-MS
  • 卡尔费休冠军国际cmp
  • 当量溶液
  • 电导率标准溶液
  • pH缓冲液
  • 农残溶剂
  • 原子吸收标准溶液
  • ICP标准溶液
  • 阴离子标准溶液
  • 无机盐
  • 其他
  • 离子对冠军国际cmp
  • 稳定同位素
  • 紫外-可见吸收光谱
  • 品牌 INFI
  • 编号 H30182
  • 规格 99.9%, SpcDry, Water≤50ppm (by K.F.), SpcSeal
  • CAS  75-05-8
  • MDL Number  MFCD00001878
  • 包装 价格 库存 - 促销价
    100mL   
    RMB    90
    500mL   
    RMB   170
    1L      
    RMB   240
    Acetonitrile	乙腈

    COA下载


  • Mol. Formula: CH3CN
  • Mol. Weight: 41.05
  • Refractive index: 1.3430 to 1.3460
  • Boiling Point: 81—82 °C ((lit.))
  • Density: 0.782 g/mL at 25 °C
  • Melting Point: -48 °C (lit.)
  • Flash Point: 10°C(lit.)
  • TSCA: Yes
  • Autoignition Point: 973 °F
  • Vapor Density: 1.41 (vs air)
  • Vapor Pressure: 72.8 mmHg
  • Solubility: MISCIBLE
  • Appearance: {Chemicalbook} liquid {...
  • Chemical Name
    Acetonitrile
    Synonym
  • Ethyl nitrile
  • RCRA waste number U003
  • Methane, cyano-
  • Methanecarbonitrile
  • 乙腈 溶液
  • CAS Number
    75-05-8
    PubChem Substance ID
    24885473
    EC Number
    200-835-2
    Beilstein Registry Number
    4124158
    MDL Number
    MFCD00001878
    Reaxys-RN
    741857
    Merck Number
    70
    Chemical Name Translation
    乙腈
    Wiswesser Line Notation
    NC1
    LabNetwork Molecule ID
    LN00162999
    GHS Symbol
    WGK Germany
    2
    Hazard Codes
  • F,Xi,Xn,T
  • Hazard statements
  • H319 Causes serious eye irritation 严重刺激眼睛
  • H225 Highly flammable liquid and vapour 高度易燃液体和蒸气
  • H302+312+332
  • H332 Harmful if inhaled 吸入有害
  • H302 Harmful if swallowed 吞食有害
  • Personal Protective Equipment
  • Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
  • RTECS
    AL7700000
    Precautionary statements
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P210280305+351+338
  • P201 Obtain special instructions before use. 使用前获取专门指示。
  • P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking. 远离热源/火花/明火/热的表面。——禁止吸烟。
  • Signal word
  • Safety Statements
  • S36/37 Wear suitable protective clothing and gloves 穿戴适当的防护服和手套;
  • S16 Keep away from sources of ignition - No smoking 远离火源,禁止吸烟;
  • Risk Statements
  • R10 Flammable 易燃
  • R11 Highly flammable 非常易燃
  • R23/24/25 Toxic by inhalation, in contact with skin and if swallowed 吸入,皮肤接触及吞食都有毒
  • R20/21/22 Harmful by inhalation, in contact with skin and if swallowed 吸入、皮肤接触和不慎吞咽有害
  • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
  • R41 Risk of serious damage to eyes 有严重损伤眼睛的危险
  • R36 Irritating to eyes 刺激眼睛
  • R24 Toxic in contact with skin 与皮肤接触有毒
  • R20/22 Harmful by inhalation and if swallowed 吸入和不慎吞咽有害
  • UN Number
  • Packing Group
    II
    Storage condition
  • 密封阴凉处保存。
  • 2-8°C
  • 免阳光和紫外线照射,4℃下冷藏保存
  • 充氩保存
  • Hazard Class
    3
    TYPE OF TEST            : TCLo - Lowest published toxic concentration
    ROUTE OF EXPOSURE       : Inhalation
    SPECIES OBSERVED        : Rodent - rat
    DOSE/DURATION           : 400 ppm/6H/2Y-I
    TOXIC EFFECTS :
       Tumorigenic - equivocal tumorigenic agent by RTECS criteria
       Liver - tumors
    REFERENCE :
       NTPTR* National Toxicology Program Technical Report Series.  (Research
       Triangle Park, NC 27709) No.206-  Volume(issue)/page/year: NTP-TR-447,1996

    TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
    ROUTE OF EXPOSURE       : Subcutaneous
    SPECIES OBSERVED        : Rodent - rat
    DOSE/DURATION           : 3500 mg/kg
    TOXIC EFFECTS :
       Details of toxic effects not reported other than lethal dose value
    REFERENCE :
       85GMAT "Toxicometric Parameters of Industrial Toxic Chemicals Under Single
       Exposure," Izmerov, N.F., et al., Moscow, Centre of International Projects,
       GKNT, 1982  Volume(issue)/page/year: -,16,1982

    TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
    ROUTE OF EXPOSURE       : Parenteral
    SPECIES OBSERVED        : Rodent - rat
    DOSE/DURATION           : 1100 mg/kg
    TOXIC EFFECTS :
       Details of toxic effects not reported other than lethal dose value
    REFERENCE :
       85GMAT "Toxicometric Parameters of Industrial Toxic Chemicals Under Single
       Exposure," Izmerov, N.F., et al., Moscow, Centre of International Projects,
       GKNT, 1982  Volume(issue)/page/year: -,16,1982

    TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
    ROUTE OF EXPOSURE       : Subcutaneous
    SPECIES OBSERVED        : Rodent - mouse
    DOSE/DURATION           : 4480 mg/kg
    TOXIC EFFECTS :
       Details of toxic effects not reported other than lethal dose value
    REFERENCE :
       85GMAT "Toxicometric Parameters of Industrial Toxic Chemicals Under Single
       Exposure," Izmerov, N.F., et al., Moscow, Centre of International Projects,
       GKNT, 1982  Volume(issue)/page/year: -,16,1982

    TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
    ROUTE OF EXPOSURE       : Intraperitoneal
    SPECIES OBSERVED        : Rodent - rat
    DOSE/DURATION           : 850 mg/kg
    TOXIC EFFECTS :
       Details of toxic effects not reported other than lethal dose value
    REFERENCE :
       JOCMA7 Journal of Occupational Medicine. (Chicago, IL)  V.1-9,    1957-67.
       For publisher information, see:JJOMDZ  Volume(issue)/page/year: 1,634,1959

    TYPE OF TEST

    {ha

    TYPE OF TEST            : Sex chromosome loss and nondisjunction
    ROUTE OF EXPOSURE       : Inhalation
    TEST SYSTEM             : Insect - Drosophila melanogaster
    DOSE/DURATION           : 131 ppm
    REFERENCE :
       MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
       Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 259,165,1991

    TYPE OF TEST            : Sex chromosome loss and nondisjunction
    TEST SYSTEM             : Yeast - Saccharomyces cerevisiae
    DOSE/DURATION           : 47600 ppm
    REFERENCE :
       MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
       Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 149,339,1985

    TYPE OF TEST            : Sister chromatid exchange
    TEST SYSTEM             : Rodent - hamster Ovary
    DOSE/DURATION           : 5 gm/L
    REFERENCE :
       EMMUEG Environmental and Molecular Mutagenesis.  (Alan R. Liss, Inc., 41 E.
       11th St., New York, NY 10003)  V.10-    1987-  Volume(issue)/page/year:
       10(Suppl 10),1,1987

    TYPE OF TEST            : TDLo - Lowest published toxic dose
    ROUTE OF EXPOSURE       : Oral
    SPECIES OBSERVED        : Rodent - hamster
    DOSE                    : 400 mg/kg
    SEX/DURATION            : female 8 day(s) after conception
    TOXIC EFFECTS :
       Reproductive - Fertility - post-implantation mortality (e.g. dead and/or
       resorbed implants per total number of implants)
    REFERENCE :
       TJADAB Teratology, The International Journal of Abnormal Development. (Alan
       R. Liss, Inc., 41 E. 11th St., New York, NY 10003)  V.1-    1968-
       Volume(issue)/page/year: 27,313,1983

    TYPE OF TEST            : TCLo - Lowest published toxic concentration
    ROUTE OF EXPOSURE       : Inhalation
    SPECIES OBSERVED        : Rodent - hamster
    DOSE                    : 8000 ppm/1H
    SEX/DURATION            : female 8 day(s) after conception
    TOXIC EFFECTS :
       Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death,
       e.g., stunted fetus)
       Reproductive - Specific Developmental Abnormalities - musculoskeletal system
    REFERENCE :
       TJADAB Teratology, The International Journal of Abnormal Development. (Alan
       R. Liss, Inc., 41 E. 11th St., New York, NY 10003)  V.1-    1968-
       Volume(issue)/page/year: 27,313,1983

    TYPE OF TEST            : TCLo - Lowest published toxic concentration
    ROUTE OF EXPOSURE       : Inhalation
    SPECIES OBSERVED        : Rodent - hamster
    DOSE                    : 5000 ppm/1H
    SEX/DURATION            : female 8 day(s) after conception
    TOXIC EFFECTS :
       Reproductive - Fertility - post-implantation mortality (e.g. dead and/or
       resorbed implants per total number of implants)
       Reproductive - Specific Developmental Abnormalities - Central Nervous System
    REFERENCE :
       TJADAB Teratology, The International Journal of Abnormal Development. (Alan
       R. Liss, Inc., 41 E. 11th St., New York, NY 10003)  V.1-    1968-
       Volume(issue)/page/year: 27,313,1983

    TYPE OF TEST            :

  • 乙腈最主要的用途是作溶剂。在石油工业中用于从石油烃中除去焦油、酚等物质的溶剂。在油脂工业中用作从动植物油中抽提脂肪酸的溶剂,在医药上用于甾族类药物的再结晶的反应介质。乙腈是医药(维生素B1),香料的中间体,是制造均三嗪氮肥增效剂的原料。也用作酒精的变性剂。此外,还可以用于合成乙胺、乙酸等,并在织物染色、照明工业中也有许多用途。
  • Polar aprotic solvent for a wide variety of reactions, including nucleophilic substitutions, oxidations, reductions and organometallic reactions. Widely used with crown ethers for the generation of 'naked' anions from their salts; see, e.g. 18-Crown-6, A11249. Preferred solvent for RuO4 oxidations, due to its coordinating ability; see Ruthenium(III)­ chloride hydrate, 11043.
  • For use in the mild conversion of amides to nitriles, see Benzamide, A10501.
  • Undergoes the Ritter reaction with alcohols or olefins in the presence of acid to give N-substituted acetamides. For benzylic alcohols, modified conditions employing boron trifluoride etherate give high yields: Synth. Commun., 24, 601 (1994). For an example, see 4-Methyl­benzyl­ alcohol, A15315.
  • Short: II/14a
  • Short: II/19a
  • Merck: 14,55 / Merck 14,70
  • 部分产品数据参考 LabNovo , 请谨慎使用并以实际实验测量值为准。