包装 价格 库存 - 促销价
25mL     RMB    60
100mL    RMB   140
500mL    RMB   520
Tetrabutylammonium fluoride
四丁基氟化铵

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  • Mol. Formula: C16H36FN·xH2O
  • Mol. Weight: 261.47(as Anhydrous)
  • Refractive index: n20/D 1.456
  • TSCA: Yes
  • Density: 0.953
  • Flash Point: -17°C(lit.)
  • Melting Point: 62-63°C
Chemical NameTetrabutylammonium fluoride
MDL NumberMFCD00011747
PubChem Substance ID 87576839
CAS Number429-41-4
Reaxys-RN3570522
Merck Number9187
Beilstein Registry Number4(4)557
Synonym
  • 四正丁基氟化铵
  • TETRABUTYLAMMONIUM FLUORIDE ON ALUMINA
  • TETRABUTYLAMMONIUM FLUORIDE (1 MOLAR SOLUTION IN THF)
  • TETRA-N-BUTYLAMMONIUM FLUORIDE HYDRATE
  • TETRA-N-BUTYLAMMONIUM FLUORIDE
  • TBAF 溶液
  • 四丁基氟化铵水合物
  • 1-Butanaminium, N,N,N-tributyl-, fluoride, hydrate
  • 氧化铝负载四丁基氟化铵
  • TBAF
  • Tetra-n-butylammonium fluoride hydrate, 98+%
  • 硅胶负载四丁基氟化铵
  • 'FLUORIDE' ON SILICA GEL
  • TETRABUTYLAMMONIUM FLUORIDE
  • TETRABUTYLAMMONIUM FLUOROIDE HYDRATE
  • TETRA-N-BUTYLAMMONIUM FLUORIDE ON SILICA GEL
  • Tetrabutylammonium Fluoride Hydrate [for Catalyst of acylation, silylation and cleavage of silyl ether]
  • 四丁基氟化铵 溶液
  • Tetrabutylammoniumfluoridehydrate,98%
  • 四丁基氟化铵
EC Number207-057-2
Chemical Name Translation四丁基氟化铵
LabNetwork Molecule IDLN00163257
WGK Germany3
GHS Symbol
Precautionary statements
  • P271 Use only outdoors or in a well-ventilated area.? 只能在室外或通风良好的地方使用。
  • P261305+351+338
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P501 Dispose of contents/container to..… 处理内容物/容器.....
  • P280305+351+338310
  • P260 Do not breathe dust/fume/gas/mist/vapours/spray. 不要吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P403+233 Store in a well-ventilated place. Keep container tightly closed. 存放在通风良好的地方。保持容器密闭。
  • P305+351+338+310
  • P310 Immediately call a POISON CENTER or doctor/physician. 立即呼救解毒中心或医生/医师。
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
  • P301+330+331+310
  • P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking. 远离热源/火花/明火/热的表面。——禁止吸烟。
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P305+351+338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. 如接触到眼睛:小心地用水冲洗几分钟。如果佩戴隐形眼镜并容易取出的话,取出隐形眼镜。继续冲洗。
  • P240 Ground/bond container and receiving equipment. 与地面接触/连接集装箱和接受设备。
  • P304+340 IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing. 如果吸入:转移到空气新鲜处,休息,保持一个适合呼吸的姿势。
  • P270 Do not eat, drink or smoke when using this product. 使用本产品时不要吃东西,喝水或吸烟。
  • P241 Use explosion-proof electrical/ventilating/lighting/…/equipment. 使用防爆电气/通风/照明/ .../设备。
  • P301+330+331 IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. 如果吞咽:漱口。不要催吐。
  • P304+340+312
  • P308+311
  • P304+340+310
Hazard statements
  • H314 Causes severe skin burns and eye damage 导致严重的皮肤灼伤和眼睛损伤
  • H351 Suspected of causing cancer 怀疑致癌
  • H225 Highly flammable liquid and vapour 高度易燃液体和蒸气
  • H335 May cause respiratory irritation 可能导致呼吸道刺激
  • H302+312+332
  • H302 Harmful if swallowed 吞食有害
Hazard Codes
  • F,C
Personal Protective Equipment
  • Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges
  • Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
Signal word
UN Number
  • 1759
  • UN2924
  • 2924
Safety Statements
  • S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护;
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后,立即用大量水冲洗并征求医生意见;
  • S27 Take off immediately all contaminated clothing 立即脱掉全部污染的衣服;
  • S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时,立即求医(可能时出示标签);
  • S16 Keep away from sources of ignition - No smoking 远离火源,禁止吸烟;
  • S33 Take precautionary measures against static discharges 对静电采取预防措施;
  • S60 This material and its container must be disposed of as hazardous waste 该物质及其容器必须作为危险废物处置;
  • S9 Keep container in a well-ventilated place 保持容器在通风良好的场所;
Packing GroupIII
Risk Statements
  • R11 Highly flammable 非常易燃
  • R19 May form explosive peroxides 可能生成易爆的过氧化物质
  • R37 Irritating to respiratory system 刺激呼吸道
  • R40 Limited evidence of a carcinogenic effect 有限证据表明其致癌作用
  • R34 Causes burns 会导致灼伤
Storage condition
  • 0-10
  • 2-8°C
  • 0-10°C
  • Hygroscopic
Hazard Class8
  • 用于酰基化,硅化反应和硅醚解理的催化剂
  • Fluoride ion as a base in organic synthesis: Chem. Rev., 80, 429 (1980). Synthetic aspects of the use of organosilicon compounds under nucleophilic catalysis conditions: Tetrahedron, 44, 2675 (1988). For a brief feature on uses of TBAF, see: Syn
  • For the cleavage of disilanes to give "metal-free" silyl anions, see Hexamethyl­disilane, A13155.
  • Merck: 14,9187
  • For nucleophilic displacement of halide or tosylate by TBAF in the preparation of alkyl and acyl fluorides, see: J. Org. Chem., 49, 3216 (1984); Org. Synth. Coll., 8, 258 (1993).
  • Mild catalyst for the silylation of OH by silazanes: Tetrahedron Lett., 35, 8409 (1994), or by hydrosilanes and disilanes: Tetrahedron Lett., 35, 8413 (1994). See Appendix 4.
  • Ester enolates can be displaced from silicon, and trapped by reaction with carbonyl compounds without ɑ-hydrogens: Tetrahedron Lett., 1699 (1976). Under similar conditions, ketones with ɑ-hydrogens are converted under kinetic control to their silyl enol ethers with high (Z)-stereoselectivity (see Ethyl­ (trimethyl­silyl)­acetate, A17707): J. Am. Chem. Soc., 98, 2346 (1976); Org. Synth. Coll., 7, 512 (1990):
  • Reagent for deprotection of N-Boc groups under mild conditions: Tetrahedron Lett., 43, 589 (2002).
  • Promotes the directed aldol condensation of silyl enol ethers with aldehydes at low temperatures under very mild conditions: J. Org. Chem., 48, 932 (1983); alkali metal fluorides give poor results.
  • Many other examples exist where the reagent acts as a base in organic synthesis:
  • Specific reagent for the cleavage of silyl ethers, including TBDMS: J. Am. Chem. Soc., 94, 6190 (1972), (see tert-Butyl­dimethyl­chlorosilane, A13064), as well as the more stable TBDPS: Org. Synth. Coll., 9, 4 (1998), and TIPS: J. Org. Chem., 45, 4797 (1980); (see also tert-Butyl­diphenyl­chlorosilane, A12721 and Chlorotriisopropyl­silane, A17376).
  • Reviews:
  • 部分产品数据参考 LabNovo , 请谨慎使用并以实际实验测量值为准。