• 超干溶剂
  • HPLC气相顶空
  • HPLC
  • LC-MS
  • 卡尔费休冠军国际cmp
  • 当量溶液
  • 电导率标准溶液
  • pH缓冲液
  • 农残溶剂
  • 原子吸收标准溶液
  • ICP标准溶液
  • 阴离子标准溶液
  • 无机盐
  • 其他
  • 离子对冠军国际cmp
  • 稳定同位素
  • 紫外-可见吸收光谱
  • 品牌 Scharlab
  • 编号 ME05031000
  • 规格 for capillary chr
  • CAS  872-50-4
  • MDL Number  MFCD00003193
  • 包装 价格 库存 - 促销价
    1L      
    RMB     0
    1-Methyl-2-pyrrolidone, for capillary chr	甲基吡咯烷酮,气相顶空

    COA下载


  • Mol. Formula: C5H9NO
  • Mol. Weight: 99.13
  • Boiling Point: 202°C(lit.)
  • TSCA: Yes
  • Melting Point: -24
  • Refractive index: 1.4680 to 1.4720
  • Density: 1.028
  • Autoignition Point: 518 °F
  • Vapor Density: 3.4 (vs air)
  • Vapor Pressure: 0.29 mmHg ( 20 °C)
  • Flash Point: 95°C(lit.)
  • Stability: 对水分敏感,充氩气保存
  • Appearance: {Chemicalbook} 无色透明油状液体,...
  • Solubility: Soluble in water (fully)...
  • Chemical Name
    1-Methyl-2-pyrrolidinone
    CAS Number
    872-50-4
    Alfabeta Name
    METHYLPYRROLIDINONE 12---
    MDL Number
    MFCD00003193
    Synonym
  • N-ME
  • {Chemicalbook}
  • N-methylpyrrolidinone
  • N-Methylpyrolidon
  • M-Pyrol
  • PubChem Substance ID
    354334395
    EC Number
    212-828-1
    Beilstein Registry Number
    21,237
    Merck Number
    6117
    Reaxys-RN
    106420
    Chemical Name Translation
    1-甲基-2-吡咯烷酮
    Wiswesser Line Notation
    T5NVTJ A
    LabNetwork Molecule ID
    LN00164397
    Warnings
  • IRRITANT
  • GHS Symbol
    WGK Germany
    1
    Hazard Codes
  • T
  • T,Xi
  • Hazard statements
  • H227 Combustible liquid 可燃液体
  • H315 Causes skin irritation 会刺激皮肤
  • H360 May damage fertility or the unborn child 可能对生育能力或未出生婴儿造成伤害
  • H319 Causes serious eye irritation 严重刺激眼睛
  • H335 May cause respiratory irritation 可能导致呼吸道刺激
  • H303 May be harmfully swallowed 吞食可能有害
  • Personal Protective Equipment
  • Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
  • Eyeshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
  • RTECS
    UY5790000
    Precautionary statements
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P305+351+338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. 如接触到眼睛:小心地用水冲洗几分钟。如果佩戴隐形眼镜并容易取出的话,取出隐形眼镜。继续冲洗。
  • P308+313 IF exposed or concerned: Get medical advice/attention. 如接触到或有疑虑:求医/就诊。
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P201 Obtain special instructions before use. 使用前获取专门指示。
  • P201261280302+352305+351+338308+313
  • P271 Use only outdoors or in a well-ventilated area.? 只能在室外或通风良好的地方使用。
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
  • P501 Dispose of contents/container to..… 处理内容物/容器.....
  • P405 Store locked up. 上锁保管。
  • P304+340+312
  • P201261305+351+338308+313
  • P305+351+338+337+313
  • P202 Do not handle until all safety precautions have been read and understood. 已阅读并理解所有的安全预防措施之前,切勿操作。
  • Signal word
  • Safety Statements
  • S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时,立即求医(可能时出示标签);
  • S53 Avoid exposure - obtain special instructions before use 避免接触,使用前获得特别指示说明;
  • Risk Statements
  • R61 May cause harm to the unborn child 可能对未出生的婴儿导致伤害
  • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
  • R45 May cause cancer 可能致癌
  • R36/38 Irritating to eyes and skin 对眼睛和皮肤有刺激性
  • R65 Harmful: may cause lung damage if swallowed 若吞咽可能伤害肺部器官
  • R10 Flammable 易燃
  • R46 May cause inheritable genetic damage 可能引起遗传基因损害
  • Storage condition
  • 易吸潮,密封避光保存。
  • Light Sensitive & Hygroscopic
  • 充氩保存
  • 2-8°C
  • Hygroscopic
  • UN Number
  • UN 1268 3/PG 3
  • TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
    ROUTE OF EXPOSURE       : Intravenous
    SPECIES OBSERVED        : Rodent - rat
    DOSE/DURATION           : 80500 ug/kg
    TOXIC EFFECTS :
       Details of toxic effects not reported other than lethal dose value
    REFERENCE :
       IYKEDH Iyakuhin Kenkyu.  Study of Medical Supplies.  (Nippon Koteisho
       Kyokai, 12-15, 2-chome, Shibuya, Shibuya-ku, Tokyo 150, Japan)  V.1- 1970- 
       Volume(issue)/page/year: 18,922,1987

    TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
    ROUTE OF EXPOSURE       : Intraperitoneal
    SPECIES OBSERVED        : Rodent - rat
    DOSE/DURATION           : 2472 mg/kg
    TOXIC EFFECTS :
       Details of toxic effects not reported other than lethal dose value
    REFERENCE :
       ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
       Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
       Volume(issue)/page/year: 26,1581,1976

    TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
    ROUTE OF EXPOSURE       : Oral
    SPECIES OBSERVED        : Rodent - mouse
    DOSE/DURATION           : 5130 mg/kg
    TOXIC EFFECTS :
       Details of toxic effects not reported other than lethal dose value
    REFERENCE :
       EPASR* United States Environmental Protection Agency, Office of Pesticides
       and Toxic Substances. (U.S. Environmental Protection Agency, 401 M St., SW,
       Washington, DC 20460)  History unknown.  Volume(issue)/page/year:
       8EHQ-1087-0695

    TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
    ROUTE OF EXPOSURE       : Unreported
    SPECIES OBSERVED        : Rodent - rat
    DOSE/DURATION           : 7 gm/kg
    TOXIC EFFECTS :
       Details of toxic effects not reported other than lethal dose value
    REFERENCE :
       34ZIAG "Toxicology of Drugs and Chemicals," Deichmann, W.B., New York,
       Academic Press, Inc., 1969  Volume(issue)/page/year: -,408,1969

    TYPE OF TEST            : LD50 - Lethal dose,

    TYPE OF TEST            : Sex chromosome loss and nondisjunction
    TEST SYSTEM             : Yeast - Saccharomyces cerevisiae
    DOSE/DURATION           : 154 mmol/L
    REFERENCE :
       EMMUEG Environmental and Molecular Mutagenesis.  (Alan R. Liss, Inc., 41 E.
       11th St., New York, NY 10003)  V.10-    1987-  Volume(issue)/page/year:
       11,31,1988

    TYPE OF TEST            : TCLo - Lowest published toxic concentration
    ROUTE OF EXPOSURE       : Inhalation
    SPECIES OBSERVED        : Rodent - rat
    DOSE                    : 150 ppm/6H
    SEX/DURATION            : female 7-20 day(s) after conception
    TOXIC EFFECTS :
       Reproductive - Effects on Newborn - growth statistics (e.g.%, reduced weight
       gain)
       Reproductive - Effects on Newborn - delayed effects
    REFERENCE :
       NETEEC Neurotoxicology and Teratology.  (Pergamon Press Inc., Maxwell House,
       Fairview Park, Elmsford, NY 10523)  V.9-    1987- Volume(issue)/page/year:
       16,241,1994

    TYPE OF TEST            : TDLo - Lowest published toxic dose
    ROUTE OF EXPOSURE       : Intraperitoneal
    SPECIES OBSERVED        : Rodent - rat
    DOSE                    : 166 mg/kg
    SEX/DURATION            : female 9 day(s) after conception
    TOXIC EFFECTS :
       Reproductive - Fertility - post-implantation mortality (e.g. dead and/or
       resorbed implants per total number of implants)
       Reproductive - Specific Developmental Abnormalities - Central Nervous System
       Reproductive - Specific Developmental Abnormalities - musculoskeletal system
    REFERENCE :
       BIRUAA Biologische Rundschau.  (VEB Gustav Fischer Verlag, Postfach 176,
       Jena DDR-6900, Ger. Dem. Rep.)  V.1-    1963-  Volume(issue)/page/year:
       14,38,1976

    TYPE OF TEST            : TDLo - Lowest published toxic dose
    ROUTE OF EXPOSURE       : Inhalation
    SPECIES OBSERVED        : Rodent - rat
    DOSE                    : 116 ppm/6H
    SEX/DURATION            : multigenerations
    TOXIC EFFECTS :
       Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death,
       e.g., stunted fetus)
    REFERENCE :
       DCTODJ Drug and Chemical Toxicology.  (Marcel Dekker, 270 Madison Ave., New
       York, NY 10016) V.1-    1977/78-  Volume(issue)/page/year: 18,271,1995

    TYPE OF TEST            : TDLo - Lowest published toxic dose
    ROUTE OF EXPOSURE       : Intraperitoneal
    S

  • 用作溶剂及萃取剂。 NMP是一种极性的非质子传递溶剂,具有毒性小,沸点高,溶解能力出众,选择性强和稳定性好的优点。广泛用于芳烃萃取;乙炔、烯烃、二烯烃的纯化。也用于聚合物的溶剂及聚合反应的介质要。如聚酰胺、聚酰亚胺、聚苯硫醚等工程塑料及芳纶纤维。另外还用于绝缘材料、农药、颜料及清洁剂等方面。
  • Short: III/35B
  • Merck: 14,6117
  • Nucleophilic displacement reactions with CN-: J. Chem. Soc., 954 (1962). Preparation of thiophenols from unactivated aryl chlorides and Na alkanethiolates: J. Org. Chem., 56, 3728 (1991). Reaction of thiophenol and potassium carbonate in uncatalyzed substitution reactions of chloroanilines and chloroanilides: J. Org. Chem., 56, 862 (1991). Synthesis of alkylaryl and alkylheteroaryl ethers, catalyzed by Cu(I): Tetrahedron, 48, 3633 (1992).
  • Water-miscible, high-boiling dipolar aprotic solvent, compare N,N-Dimethyl­formamide, A13547 and Dimethyl­ sulfoxide, A13280, used in a wide variety of reactions, e.g.:
  • Short: III/35D3
  • Merck: 14,6117 Beilstein:21,237
  • 部分产品数据参考 LabNovo , 请谨慎使用并以实际实验测量值为准。